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The opioid crisis has become an increasingly pressing issue in recent years, with opioid addiction affecting millions of lives worldwide. Numerous treatment options have emerged to tackle this epidemic, but none have gained as much attention as Vivitrol. So, does Vivitrol work? Yes, Vivitrol works by binding to the brain’s opioid receptors. In this article, we will delve into the science behind Vivitrol, its effectiveness in treating opioid addiction, and the factors that may impact its efficacy.

Does Vivitrol Work?

Vivitrol, generically known as naltrexone, is a prescription medication approved by the FDA for the treatment of opioid dependence and alcohol use disorder. It comes in the form of a once-a-month injection and is intended to be used in conjunction with behavioral therapy and counseling. Vivitrol works by blocking the effects of opioids in the brain, effectively preventing the patient from experiencing the pleasurable sensations typically associated with drug use. By doing so, Vivitrol aims to reduce cravings and promote long-term recovery from addiction.

How Does Vivitrol Work In The Brain?

To understand how Vivitrol works, we must first explore the brain’s opioid receptors. These receptors, which are primarily found in the brain, spinal cord, and gastrointestinal tract, are responsible for mediating the effects of opioids. When a person takes an opioid, it binds to these receptors, triggering a release of dopamine and other neurotransmitters that produce feelings of euphoria, pain relief, and relaxation.

Vivitrol is an opioid antagonist, meaning that it binds to the opioid receptors without activating them. By doing so, it essentially blocks the receptors from being activated by opioids. As a result, individuals who use opioids while on Vivitrol will not experience the typical pleasurable sensations associated with drug use. This blockade helps to deter patients from using opioids, ultimately reducing cravings and promoting recovery.

Vivitrol’s Efficacy in Treating Opioid Addiction

Several clinical trials and research studies have been conducted to evaluate the effectiveness of Vivitrol in treating opioid addiction. Overall, these studies have demonstrated positive results, with Vivitrol proving to be an effective tool in reducing opioid use, relapse rates, and cravings.

One notable study published in The Lancet in 2017 compared the efficacy of Vivitrol to buprenorphine, a commonly prescribed medication for opioid addiction treatment. The study found that patients receiving Vivitrol had a similar rate of opioid-negative urine samples compared to those receiving buprenorphine. Moreover, the Vivitrol group reported lower cravings for opioids than the buprenorphine group.

In another study published in the Journal of Substance Abuse Treatment in 2016, researchers found that patients receiving Vivitrol had significantly lower relapse rates and higher treatment retention rates compared to a placebo group.

It is important to note, however, that Vivitrol is not a one-size-fits-all solution. Its efficacy may vary depending on individual factors such as the severity of the addiction, the patient’s commitment to recovery, and the level of support received during treatment.

Factors That Impact Vivitrol’s Efficacy

  1. Detoxification: Before initiating Vivitrol treatment, clients must undergo a detox. This typically involves a period of 7 to 10 days without any opioid use and round-the-clock supervision of medical staff. If a client receives Vivitrol before completing detox, they may experience precipitated withdrawal, which can be extremely uncomfortable and potentially dangerous.

  2. Adherence to treatment: The effectiveness of Vivitrol depends on the patient’s commitment to receiving the injections consistently and attending regular therapy sessions. Skipping doses or not adhering to the prescribed treatment plan can diminish Vivitrol’s efficacy.

  3. Support system: A strong support system is crucial for a successful recovery. This may include family, friends, healthcare professionals, and support groups. Patients who have a solid support system in place are more likely to stay committed to their treatment plan and achieve better outcomes with Vivitrol.

  4. Counseling and behavioral therapy: Vivitrol is intended to be used in conjunction with behavioral therapy and counseling. These therapeutic approaches help patients develop coping strategies, address underlying issues contributing to addiction, and establish a foundation for long-term recovery. Patients who actively participate in counseling and therapy while on Vivitrol are more likely to see positive results. While there are many different forms of therapy, intensive outpatient programming or a higher level of care is often recommended.

  5. Co-occurring mental health conditions: Many individuals struggling with opioid addiction also have co-occurring mental health disorders, such as depression or anxiety. The presence of these conditions can impact the effectiveness of Vivitrol, as they may exacerbate cravings or impede recovery. Addressing these co-occurring disorders through integrated treatment plans can improve the overall efficacy of Vivitrol in a Georgia dual diagnosis treatment center.

  6. Individual factors: Each person’s journey with addiction is unique, and individual factors such as genetics, environment, and personal history can influence the efficacy of Vivitrol. Some patients may respond better to the medication than others, which highlights the importance of individualized treatment plans tailored to each person’s needs.

Find Addiction Treatment in Atlanta Today

So, if you’re still wondering, “does vivitrol work?” Yes, Vivitrol has proven to be an effective treatment option for opioid addiction when used as part of a comprehensive treatment plan. By blocking the effects of opioids in the brain, Vivitrol helps to reduce cravings and promote long-term recovery. At Buckhead Behavioral Health, we provide personalized addiction treatment in Atlanta help clients find lasting recovery from substance use disorder with medication, therapy, and support. Call us now at (470) 460-6789 or learn about your rehab insurance coverage today!

Erika Dalton, LMSW

Erika brings over a decade of clinical experience to Buckhead Behavioral Health. After starting as one of the first employees at Creekside Recovery Residences, Erika now works as Executive Director, leading program development across Creekside and sister company Buckhead Behavioral Health. She specializes in treating addiction, mood disorders, co-occurring disorders, trauma and challenges related to life transitions. Her extensive clinical experience includes cognitive behavioral therapy (CBT), dialectical behavioral therapy (DBT), expressive therapy, 12-Step concepts, motivational interviewing, solution-focused strategies and culturally competent interventions. Erika earned her bachelor’s degree in psychology from Georgia State University and graduated with honors from Walden University with a master’s degree in social work. She has witnessed the devastation that addiction and mental illness can create in the lives of individuals and families and is an ardent believer in human beings’ innate resilience and capacity for positive change. Find Erika on LinkedIn